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At Roche, we are working to make next-generation sequencing simple and accessible enough for routine use. By accelerating clinical research, streamlining workflows, and expanding assay menus, we are broadening access to genomic data and lowering barriers to adoption. From robust sample isolation and preparation tools to novel sequencing technology and advanced bioinformatics, we are developing differentiated, highly integrated end-to-end solutions for next-generation sequencing, resulting in a sample in, result out workflow.

Our Systems Technology Group, a part of Roche Sequencing Solutions, is focused on creating and advancing technologies to significantly enhance DNA sequencing workflows. We are seeking a Senior Engineering Manager to drive the prototyping activities for our advanced hardware concepts and platforms in the Research and Early Development stages. This is a critical, hands-on leadership role for an engineer who is passionate about pioneering new technologies and can bridge the gaps between ambitious design concepts and cutting-edge, functional instrumentation. We are seeking an accomplished technical leader and multi-disciplinary expert to partner closely with our lead design engineers, chemists and integration team to translate their designs, chemistry and workflows into robust, fully integrated prototype solutions.
 

Core Responsibilities:

You will lead the design, fabrication, assembly, bring-up, verification and support of early-stage instruments, breadboards, fixtures and prototypes in a fast-paced R&D environment, ensuring seamless integration with the chemistry and workflows.

You will serve as a key technical partner to principal design engineers by translating their concepts and designs into functional systems and providing input and alternative solutions as well as feedback on manufacturability, serviceability, and performance to influence future designs and iterations.

You will recruit, build, train and lead a world-class R&D hardware team, fostering a culture of strong work ethics and engineering rigor

You will serve as a hands-on contributor, leading by example to solve tough technical challenges, especially during the crucial initial team building phases.

You will lead or perform proof-of-concept testing and technology down-selection activities. This may include evaluating, testing, and iterating on novel features and modules, bringing them from early concepts and design to functional components and sub-systems.

You will own and advance our tools and code base for hardware simulation, control, verification and characterization efforts

You will be responsible for procurement of parts and all necessary equipment and tools for in-house fabrication and testing. This may also include identifying, evaluating and onboarding new vendors and suppliers.

You will own key documentation for our hardware platforms, such as BOMs, assembly instructions, test plans/reports, troubleshooting guides, and configuration management records

You will identify and champion new products, processes and technologies, contributing to the strategic direction of the R&D organization.

This is an onsite position based in Santa Clara, CA.

Relocation benefits are not being offered for this role.

Who You Are (Required):

You have a PhD in Mechanical Engineering, Electrical Engineering, Bioengineering, or a related discipline with at least 9 years of relevant industry experience; OR a Master's degree with at least 11 years of relevant industry experience; OR a Bachelor's degree with at least 13 years of relevant industry experience.

You have demonstrated deep, hands-on expertise designing, building, testing and troubleshooting complex life science breadboards, fixtures or prototype instruments with such as DNA sequencers, flow cytometers, DNA synthesizers, HPLC systems involving fluidics, pneumatics, thermal systems, and mechatronics. 

You have demonstrated expertise in SolidWorks, fabrication and rapid prototyping tools/techniques

You have demonstrated leadership skills and strong interpersonal and communication skills with the ability to communicate technical knowledge in a clear and understandable manner; you excel at problem-solving skills and the ability to work under ambiguous situations

You have excellent organizational skills, including the ability to efficiently evaluate, prioritize and handle multiple changing projects and priorities; you complete work in a timely, accurate and thorough manner
 

Who You Are: (Preferred)

You have demonstrated the ability to solve unique or unprecedented issues that span hardware, software, chemistry, process and consumables

You have direct experience with microfluidic systems, including design, microfabrication and control

You have experience using Linux operating systems for hardware control

You have expertise in Python for hardware control, data acquisition, and data analysis

You have expertise with Git, Jira and Confluence

You have experience troubleshooting board-level electrical issues

You have experience with optics and machine vision

You work with a sense of urgency, optimism and natural scientific/engineering curiosity

You have a desire to learn and be challenged, to always seek out new challenges, and to challenge the status quo

The expected salary range for this position based on the primary location of Santa Clara, CA is $152,500 - $283,000.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance. 

This position also qualifies for the benefits detailed at the link provided below.

Benefits

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A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

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