St. Louis, Missouri, USA
1 day ago
Senior Associate Scientist; Downstream Process Development-Conjugation

Use Your Power for Purpose

As a Senior Associate Scientist, you will help Pfizer develop new and improved processes used in the research and development of our drugs. The purpose of the Senior Associate Scientist position is to provide the planning and execution of experiments designed to aid in defining manufacturing processes for biopharmaceuticals. The successful candidate will have a working knowledge of biochemistry and related analytical chemistry, bioconjugation, chromatography, and filtration design principles. This position requires the design and execution of experiments using these technologies and the ability to evaluate and clearly report the results to laboratory colleagues and other affected functional areas.

What You Will Achieve

The successful applicant will join a larger team of scientists across multiple sites focused on developing scalable, robust, efficient, and innovative biochemical and purification processes suitable for clinical material production and commercialization.

Responsibilities will include small-scale studies and support transfers to pilot and commercial facilities.

This position will be expected to develop and test new hypotheses to improve the fundamental understanding of bioconjugation and purification processes.

This position will support process validation, quality by design, regulatory approaches, and quality systems.

This position will be expected to contribute to the preparation of technical reports and external publications and make oral presentations to scientists and management.

Performs all duties associated with the operation of effective research laboratories.

The successful candidate must be able to endorse change to business infrastructure to ensure pipeline, legacy and technology success.

Qualifications

Must Have

BS with 2 to 4 years pf experience or MS with 0-2 years in a biological or engineering discipline (Biochemistry, Biotechnology, Chemical/Biochemical Engineering or equivalent).

Knowledge in process development of biological candidates, scale-up, technology transfer and/or bioprocess manufacturing.

A good understanding of protein chemistry, protein analytics, and bioprocess technology is required.

Demonstrated ability to drive for results and generate innovate research independently.

Applicant should be self-motivated, organized, and capable of working independently, and in collaborative and diverse teams.

The successful candidate will possess strong oral and written communication skills.

Nice to Have

Knowledge of bioconjugation, organic chemistry, and characterization methods.

Familiarity with proteins/biomolecules purification techniques.

Familiarity with HPLC and analytical method troubleshooting.

Familiarity with GLP/GMP requirements.

Experience transferring Biotherapeutic processes to pilot plants or manufacturing organizations.

Sound understanding of statistical experimental design and analysis is desirable.

Experience with programming languages, such as Visual Basic for Application (VBA), Python, and/or other languages.

Ability to work effectively in a team environment

Strong organizational and time management skills

Other Job Details 

Work Location Assignment: On Premise


The annual base salary for this position ranges from $66,500.00 to $110,900.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.  These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.  This position requires permanent work authorization in the United States.

Research and Development

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