Lexington, Massachusetts, USA
3 days ago
Research Scientist II

Description

Develop advanced and robust LC-MS analytical methods for the bioanalysis of different molecular formats such as small molecules, oligonucleotides, peptides, and/or proteins.

Develop and implement innovative high-resolution mass spectrometry-based metabolite profiling and identification platforms

Perform LC-MS-based small molecule biomarker analysis occasionally

Review and translate complex LC-MS-based data sets and articulate findings to project teams

Maintain/document records of all experiments, including QC review data, experimental results, and reports as appropriate into electronic laboratory notebooks

Contribute to the team’s knowledge through updating scientific literature and discussions

Maintain and troubleshoot lab instruments such as biological sample extraction systems, HPLC, and LC-MS

Additional Skills & Qualifications

1. PhD or Master’s degree in pharmaceutical sciences, analytical chemistry, chemistry or related disciplines with relevant bioanalysis experience from industry or academia required. (Fellowship work can be counted as relevant experience, but preference will be given to a scientist with CRO bioanalysis experience)

1.\tStrong LC-MS bioanalysis experience with method development and troubleshooting.

2.\tHands-on with at least one MS (Mass Spec) platform (e.g., Sciex 6500/7500, Thermo QE-HF, Q-Exactive, Q-TOF 4800).

3.\tPhD with 3–5 years of experience

4.\tExperience in oligonucleotide research and bioanalysis.

5.\tStrong LC-MS skills required; ADME/PKPD experience is a plus.

7.\tOpen to relocation at own expense if able to meet the start date.

8.\tPrioritize method development experience over routine sample analysis.

9.\tFamiliarity with Analyst (Sciex), Xcalibur (Thermo), or similar software.

11.\tClear communicator with a long-term contributor mindset.

Experience Level

Intermediate Level

Pay and Benefits

The pay range for this position is $45.00 - $48.00/hr.

Eligibility requirements apply to some benefits and may depend on your job
classification and length of employment. Benefits are subject to change and may be
subject to specific elections, plan, or program terms. If eligible, the benefits
available for this temporary role may include the following:

• Medical, dental & vision
• Critical Illness, Accident, and Hospital
• 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available
• Life Insurance (Voluntary Life & AD&D for the employee and dependents)
• Short and long-term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation or Sick Leave)

Workplace Type

This is a fully onsite position in Lexington,MA.

Application Deadline

This position is anticipated to close on Aug 13, 2025.

About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.

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