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Position Summary:

We have an exciting opportunity to join our team as a Research Scientist. The Rodent Genome Engineering Lab (RGEL) is a fee-for-service core facility at NYU Langone Health, providing innovative resources to biomedical researchers. We are seeking a Microinjection Specialist (Research Scientist) to expand the cores transgenic model services. This onsite role focuses on generating complex genomically engineered mouse models in close collaboration with Dr. Jef Boeke at the Institute for Systems Genetics (NYULH). The Research Scientist will report to RGELs Associate Director.

Key responsibilities include executing research projects to produce genomically engineered mice using mouse embryonic stem cell (mESC) chimeric blastocyst microinjection and embryo transfer. The role involves mESC culture, blastocyst injection, rederivation, cryopreservation, in vitro fertilization, and sperm cryopreservation. The scientist will also maintain breeding colonies and detailed records.
The ideal candidate will perform both routine and advanced laboratory techniques, contribute to method development, and uphold high-quality standards in transgenic support services. The position requires independent planning and execution of experiments, animal model management, and timely completion of assigned projects.

Job Responsibilities:

Independently generate chimeric mice for service projects designed by the principal investigators, including all scheduling, animal handling, microinjection, and associated tasks. Work with RGELs Director and Associate Director, as well as with Dr. Boeke to develop enhanced methods and protocols for transgenic mouse generation. Document progress and generate timely reports and presentations. Independently perform mouse rederivation, including sperm cryopreservation. Independently perform mouse handling tasks, including hormone injection (PMSG, HCG), superovulation, mating, and weaning. Independently perform euthanasia of mice and collection of blastocysts or zygotes. Independently inject mouse embryonic stem cells into mouse blastocysts to generate chimeric mice. Independently perform rederivation of mouse strains to specific pathogen-free status. Independently perform embryo oviduct transfer. Monitor daily animal health and welfare. Demonstrates knowledge of the organization's core values and incorporates them into the performance of duties. Maintain required attendance level and adherence to the work schedule in accordance with the required staffing levels to ensure that assigned duties are completed. Responsible for the maintenance and upkeep of all instruments and laboratory facilities, core laboratory procedures and practices, including quality control and compliance. Maintains confidentiality of all research information. Provides guidance, cooperates, communicates and related well to all levels of NYULH staff. Listens carefully to others, responds appropriately, answers questions or obtains needed information. Communicates ideas, problems, suggestions and messages in a timely and effective manner. Performs other related duties as assigned.

Additional Position Specific Responsibilities:

Communication and Relationship to Other Staff:
1. Maintain confidentiality of all research information
2. Excels in cooperation, collaboration and communication with all NYULH employees
3. Communicate professionally and precisely with staff and clients
4. Maintain a professional working relationship with all staff and clients
5. Communicate ideas, problems, and suggestions in a timely and effective manner
Judgement/decision-making:
1. Is able to recognize problems as they occur, and through the application of appropriate policy/procedure, determines and/or recommends the appropriate solution. Must be able to troubleshoot.
2. Seeks guidance as necessary for the performance of duties; asks appropriate questions when in doubt and utilizes reference sources/materials to ensure accuracy.
3. Advises appropriate personnel of situations/problems requiring intervention or follow-up attention.

Minimum Qualifications:

To qualify you must have a MS degree and 2-4 years of experience.

Preferred Qualifications:

This is a senior level position. 3-5 years of laboratory animal experience in an AAALAC accredited transgenic core facility and direct experience with mouse microinjection procedures are highly preferred. An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.

Qualified candidates must be able to effectively communicate with all levels of the organization.

NYU Grossman School of Medicine provides its staff with far more than just a place to work. Rather, we are an institution you can be proud of, an institution where you'll feel good about devoting your time and your talents. At NYU Langone Health, we are committed to supporting our workforce and their loved ones with a comprehensive benefits and wellness package. Our offerings provide a robust support system for any stage of life, whether it's developing your career, starting a family, or saving for retirement. The support employees receive goes beyond a standard benefit offering, where employees have access to financial security benefits, a generous time-off program and employee resources groups for peer support. Additionally, all employees have access to our holistic employee wellness program, which focuses on seven key areas of well-being: physical, mental, nutritional, sleep, social, financial, and preventive care. The benefits and wellness package is designed to allow you to focus on what truly matters. Join us and experience the extensive resources and services designed to enhance your overall quality of life for you and your family.

NYU Grossman School of Medicine is an equal opportunity employer and committed to inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration. We require applications to be completed online.

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NYU Langone Health provides a salary range to comply with the New York state Law on Salary Transparency in Job Advertisements. The salary range for the role is $58,500.00 - $80,850.00 Annually. Actual salaries depend on a variety of factors, including experience, specialty, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.

To view the Pay Transparency Notice, please click here