RESEARCH INVESTIGATOR Apply Now **How to Apply** A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position. **Responsibilities*** The Department of Pathology at Michigan Medicine has an open Research Investigator position to join our faculty in Ann Arbor, MI. Successful candidate will focus on advancing DALTAC technology; selective proximity=inducing degraders that simultaneously inactivate AR and p300/CBP as a therapeutic strategy. Be able to use multi-omic approaches and vivo modeling. Define mechanisms of action, assess resistance mechanisms, and identify predictive biomarkers. Expand efforts on synthetic lethality in CKD12 deficient tumors. This person will lead projects that explore combinatorial degrader strategies. They will also provide experienced hands-on leadership and supervision to more junior lab members. **Required Qualifications*** + This position requires a PhD + Must be an experienced researcher, with at least 5 years + Have hands-on experience with leadership and supervision + Must have experience with Translational Prostate Cancer Research. + Experience on p300/CBP-mediated enhancer acetylation in prostate cancer. **Modes of Work** Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about thework modes (https://hr.umich.edu/working-u-m/my-employment/ways-we-work-resource-center/ways-we-work-implementation-group/modes-work) . **Background Screening** Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses. **Application Deadline** Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended. **U-M EEO Statement** The University of Michigan is an equal employment opportunity employer. **U-M EEO Statement** The University of Michigan is an equal employment opportunity employer. **Job Detail** **Job Opening ID** 267111 **Working Title** RESEARCH INVESTIGATOR **Job Title** RESEARCH INVESTIGATOR **Work Location** Ann Arbor Campus Ann Arbor, MI **Modes of Work** Onsite **Full/Part Time** Full-Time **Regular/Temporary** Regular **FLSA Status** Exempt **Organizational Group** Medical School **Department** MM Pathology Department **Posting Begin/End Date** 8/07/2025 - 8/14/2025 **Career Interest** Primary Apply Now