**Position Summary** We are seeking an accomplished Principal Scientist with broad biologics knowledge and technical leadership expertise to drive global R&D projects through internal–CRO hybrid models. In this role, you will be a subject-matter expert for biologics discovery, engineering, and relevant technology platforms, validating new approaches and ensuring accelerated program delivery in areas such as oncology, immunology, ophthalmology, or CNS. Success requires managing multidisciplinary teams and external resources, applying advanced scientific and project skills to validate and co-lead biologics programs from concept to key milestones. **Key Responsibilities** 1. **Global Program Leadership & Workflow Acceleration** • Serve as scientific lead or co-lead on critical biologics projects, partnering with internal teams and CROs to ensure timely and efficient execution. • Oversee hybrid workflows (internal + external) that integrate novel biologics technologies into therapeutic pipelines. 2. **Platform Validation & Subject-Matter Expertise** • Provide expert technical input on various biologics modalities (antibody, RNA therapeutics, etc.). • Validate relevant technology platforms to address unmet needs, guiding teams on their applicability and proper deployment within global programs. 3. **CRO Management & Collaboration** • Coordinate external CRO partnerships—defining project scopes, deliverables, and timelines—to maximize efficiency and quality. • Ensure smooth communication, alignment of objectives, and proactive issue resolution between internal stakeholders and external resources. 4. **Mentorship & Innovation** • Mentor junior scientists, fostering technical excellence, knowledge-sharing, and continuous improvement. • Encourage the adoption of innovative approaches (e.g., AI-driven screening, automated workflows) that streamline biologics R&D. **Qualifications** **Educational Background & Experience** • Ph.D. in Immunology, Biochemistry, Bioengineering, or a related discipline; extensive industrial or advanced research experience strongly preferred. • 8+ years of hands-on experience in biologics R&D (e.g., multi-specific antibodies, ADC design, siRNA/mRNA, or CAR-T platforms). • Demonstrated success managing complex projects or programs, ideally involving CRO partnerships in a global context. **Technical & Scientific Expertise** • Deep knowledge of at least one key biologics modality, plus familiarity with complementary technologies. • Proven ability to evaluate, validate, and implement new platforms or methodologies—balancing scientific rigor with practical timelines. • Track record of scientific contributions (publications, patents, internal milestones) showcasing problem-solving in advanced biologics. **Program & Collaboration Skills** • Skilled in leading/co-leading cross-functional teams, aligning internal capabilities with CRO deliverables. • Strong organizational and project management abilities, ensuring milestones are met and resources are efficiently deployed. • Clear communicator who can translate technical discussions into actionable plans for diverse stakeholders (scientists, project managers, leadership). **Innovation & Mentorship** • Adept at driving novel solutions (e.g., AI-based screening, automation) to accelerate biologics research. • Committed to developing talent, sharing expertise, and creating a culture of continuous innovation and collaboration. **Pursue** **_progress_** **, discover** **_extraordinary_** Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) ! Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi (https://youtu.be/96EwNjb1TLo) As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live. All in for Diversity, Equity and Inclusion at Sanofi - YouTube (http://www.youtube.com/watch?v=SkpDBZ-CJKw&t=2s)