Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

In Discovery Pharmaceutics and Analytical Sciences, you will have the ability to impact the lives of patients by working with multidisciplinary research teams to help discover novel, efficacious and safe therapeutics. BMS is looking for a motivated Principal Scientist with a desire to contribute to the fast paced discovery matrix environment by conducting biophysical characterization and preformulation studies for potential new biologic candidates. The ideal candidate would have a good understanding of analytical techniques of molecules, as well as biophysical properties of new biologic candidates as they relate to compound liability and developability profiles.

Job Responsibilities

Ability to carry out and interpret data from biophysical characterization and preformulation studies on potential new biologics candidates, with the purpose to define their developability and liability profiles.Provide experimental and computational input to protein discovery scientists during design and screening of new biologics entities and enable drug design from lead optimization to the point of candidate identification, characterization and selection.Strategically design and guide the development of formulations suitable for use in drug discovery pharmacology studies, PK studies and initial exploratory toxicology studies.Work in conjunction with discovery teams to enable drug discovery through application of innovative drug delivery technologies or devices, internally and externally, enabling more effective delivery of biologics.Participate in and drive strategic direction of the Discovery Pharmaceutics & Analytical Sciences group to further its ability to act as a problem solving entity for biologics discovery teams and provide seamless transfer of candidates to development.Advance the abilities of the larger candidate optimization organization to develop expertise in scientific areas which can enable our understanding of the role of biophysical properties in the overall biopharmacetuical performance of proteins, antibodies and other large molecule modalities.

Job Requirements/Education

PhD with 4+ years or a B.S/M.S with more than 8 years of experience in industry in Pharmaceutical/ Protein/Analytical Chemistry, or academic equivalent, is required.Knowledge of basic protein chemistry and biopharmaceutical principles as they apply to drug discovery and drug delivery of proteins, antibodies and other large molecule modalities is required.Understanding of biophysical properties and analytical methods used for characterization of proteins and other large molecules and how they relate to the biologics’ in vivo delivery and disposition is required.Experience in protein and peptide chromatography and application of various modes of UPLC/HPLC, mass-spec based protein footprinting techniques, peptide mapping, glycosylation and PTM analysis of proteins using mass spectrometry.Strong understranding of preformulation aspects for proteins, antibodies and other large molecules is necessary along with ability to guide the generation and interpretation of preformulation data as it relates to the overall discovery process.An understanding of drug delivery technology/ devices and its assessment relative to the delivery of biologics is desired.Good written and verbal communication skills are a must.Excellent interpersonal skills demonstrating effectiveness as a team player on multidisciplinary teams resourced in a flexible and global environment is required.The ability to think innovatively and reduce such thinking to practical implementation enabling the discovery and design of new biologics entities is desired.Knowledge on use of computers and databases for data collection, compilation, analysis and information dissemination is a must.

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

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