At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com **Job Function:** Discovery & Pre-Clinical/Clinical Development **Job Sub** **Function:** Clinical Development & Research – Non-MD **Job Category:** Scientific/Technology **All Job Posting Locations:** Horsham, Pennsylvania, United States of America, Raritan, New Jersey, United States of America, Spring House, Pennsylvania, United States of America **Job Description:** About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine We are searching for the best talent for a Principal Scientist, MSAT – Advanced Therapies that can be in either Raritan, NJ, Spring House, PA or Horsham, PA. Purpose: The Principal Scientist we are seeking will be responsible for leading Advanced Therapies manufacturing projects, including product introduction, tech transfer, validation, and providing routine manufacturing support. He/She will also be responsible for projects that will drive reliability, innovation and sustainability in our processes and plants, both internally and externally. In this role, he/she will partner with R&D, Quality, and Regulatory to ensure processes meet the needs of today and tomorrow. The Principal Scientist can shape, can work in close collaboration with other roles, and must have strong communication skills to influence other functions/levels outside of own group. In this role you will effectively lead global and cross organizational teams to generally attain desired results for all parties. Strong knowledge of cell and gene manufacturing processes is a must. Hands-on experience in both R&D and Manufacturing Operations is highly desirable. Proven experience with technical documentation will be required. Key Responsibilities: • Lead and coordinate biopharmaceutical manufacturing projects, including but not limited to tech transfer and process validation activities. • Utilize detailed technical knowledge of manufacturing unit operations and conduct complex investigations and FMEA for manufacturing or life-cycle management. • Demonstrate strong communication and organizational skills to effectively influence and collaborate with peers, superiors, and external partners in a dynamic, highly-matrixed environment. Qualifications: Required: • Bachelor degree in biotechnology, chemistry, engineering, or related area. Master’s and PhD degree is a plus with Demonstrated experience in biopharmaceutical manufacturing across all stages of the product life cycle development. • Principal Scientist level will require proven experience in the biopharmaceutical development or manufacturing arena for 6-8 years of experience. • Detailed technical knowledge of manufacturing site unit operations with a preference for cell and gene therapy manufacturing. • Experience leading the coordination of tech transfer activities and technical services. • Experience leading the coordination of process validation activities. • Strong communication and interpersonal skills, with the ability to work independently and in a team environment. • Experience leading complex investigations using a variety of RCA tools. • Experience leading FMEAs for process change, technology transfer and material qualification. • Good knowledge of GMP, Q&C and regulatory requirements. • Ability to influence and lead peers, superiors, and external partners. • Experience working in a large, highly matrixed environment. • Flexibility to adapt to changing situations and priorities and to provide problem resolution. • Excellent organizational skills across multiple work streams with the ability to plan and anticipate deadlines and deliverables. Preferred: • Experience with manufacturing scale out, including capacity protocols and execution. • Experience with aseptic processing simulations, process closure and Annex 1 requirements. • Experience with MES, LIMs, data automation IT architecture is a plus. • Experience with facility design, layouts and essential utilities is a plus. Other: • Fluent in written and spoken English • 10-25% travel may be required, depending on project needs. • 15-30% of occasional person in plant responsibilities. Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource. The anticipated base pay range for this position is $115,000 to $197,800. **The anticipated base pay range for this position is :** $115,000 to $197,800. Additional Description for Pay Transparency: The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation’s performance over a calendar/performance year. Bonuses are awarded at the Company’s discretion on an individual basis. Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)). Employees are eligible for the following time off benefits: Vacation – up to 120 hours per calendar year Sick time - up to 40 hours per calendar year Holiday pay, including Floating Holidays – up to 13 days per calendar year of Work, Personal and Family Time - up to 40 hours per calendar year Additional information can be found through the link below. https://www.careers.jnj.com/employee-benefits The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market.