Principal Scientist, Molecular Modelling & Structural Biology Requistion ID: 6296 Location: Copenhagen, Danish Capital Region, DK **Principal Scientist, Molecular Modelling & Structural Biology** Are you ready to make an impact on drug discovery? We are seeking a skilled Computer-Aided Drug Discovery modeller to join our team. **Your new role** Your main responsibilities will be to drive drug discovery projects by identifying, developing, and delivering high quality modelling approaches and hypothesis for design in a timely manner. You will be directly involved in the drug discovery project teams, where you will proactively lead modelling by using innovative approaches, including physics-, and ML/AI-based methods for prioritization and design. You will have a high impact on drug discovery campaigns by driving project strategies, from hit finding, lead optimization and drug candidate selection. **Your future team** The Molecular Modelling & Structural Biology team is working closely together with Medicinal Chemistry and Biotherapeutic Discovery. You will join a team of 6 scientists with different backgrounds, all contributing with their expertise to build a dynamic team advancing Lundbeck’s drug discovery projects. We are responsible for Modelling/Computer-Aided Drug Design and Structural Biology supporting multiple modalities. We are fully integrated in the discovery process, working in multi-disciplinary chemistry or biologics projects from early-stage hit-finding, lead optimization, to candidate selection. The position is based in Copenhagen, Denmark. **What you bring to the team** + You are an experienced, collaborative, and communicative modeller with a proven history of impact in drug discovery projects. + You have a PhD in Computational Chemistry, Computational Structural Biology, or related field and several years of experience in Pharmaceutical Industry, comprehensive knowledge and experience with most Computer-Aided Drug Design concepts and techniques, including ML/AI- and Physics-based methods using industry standard modelling tools, MD simulations, FEP, and AlphaFold. + You have extensive experience in small molecule drug discovery, or protein/antibody engineering, including solving antibody engineering related challenges, like humanization, immunogenicity, and developability. **Our promise to you** Lundbeck offers an inspiring workplace and innovative culture, where our curiosity, accountability and adaptability enable us to transform lives. We want to go faster and further on addressing the big unmet needs of people living with brain disorders. We offer rewarding careers with a mix of exciting tasks and development opportunities that are balanced with initiatives focused on your well-being. We need every brain in the game, and at Lundbeck, we are committed to building a workforce that is as diverse as the people we serve. Read more about our commitment at www.lundbeck.com/global/about-us/our-commitment/diversity-and-inclusion . **Apply now** Can you see yourself in this role? We want to hear from you. Does this sound like your dream job, but you’re not sure if you meet all the requirements? We still want to hear from you! Upload your CV and include a few lines about your motivation for applying. We ask you not to include a photo or personal information that does not relate to your professional experience. If you have questions, please contact Henrik Keränen, Senior Manager, 30832875 Applications must be received by August 13th 2025. Learn more about us at www.lundbeck.com ,LinkedIn (https://www.linkedin.com/company/lundbeck/) or Instagram (@h_lundbeck). **\#EveryBrainInTheGame** **_This job ad is intended for individuals seeking a career opportunity with Lundbeck._** _We engage with recruitment and search firms where needed on the basis of a written agreement, and we do not accept unsolicited requests of any kind. If you work as a recruitment consultant, you are kindly instructed to refrain from contacting Lundbeck or the hiring manager directly with suggested candidates. If you violate this policy, you do so at your own risk and for your own account, and Lundbeck will not assume any liability nor pay any associated fees resulting from such violation._ **About Lundbeck** At Lundbeck, our most important contribution is easing the burden of the millions of people living with brain disorders. Whether it is migraine, depression, or other brain disorders, patients, their carers, and society as a whole depend on us. Through cutting edge science and strong partnerships, we develop and market some of the world’s leading treatments, expanding into neuro-specialty and neuro-rare from our strong legacy within psychiatry and neurology. The brain health challenge is real. Our commitment is real. Our impact is real. **About Lundbeck** At Lundbeck, our most important contribution is easing the burden of the millions of people living with brain disorders. Whether it is migraine, depression, or other brain disorders, patients, their carers, and society as a whole depend on us. Through cutting edge science and strong partnerships, we develop and market some of the world’s leading treatments, expanding into neuro-specialty and neuro-rare from our strong legacy within psychiatry and neurology. The brain health challenge is real. Our commitment is real. Our impact is real.