A fellow postdoctoral position is available in the laboratory of Dr. Jason M. Schenkel in the Department of Immunology, at The University of Texas MD Anderson Cancer Center. The Schenkel lab is focused on understanding the immune response to both cancer and inflammation. Specifically, the Schenkel Lab is interested in understanding the role of the tissue, tumor microenvironment, and inflammatory cues in shaping CD8+ T cells differentiation and migration, how this response changes over time, and how metastatic disease alters the composition of local and systemic immune cells. The majority of this work will be carried out in pre-clinical mouse models of cancer and inflammation; however, the laboratory will extend our findings into primary human samples in the future. Candidates for this position will have the opportunity to work on sophisticated models of cancer in a positive work environment with an energized group of individuals and with ample access and mentoring by Dr. Schenkel. *LEARNING OBJECTIVES* 1) To understand the role of the tissue and tumor microenvironment in driving T cell and leukocyte dysfunction in tumors. 2) To determine the role of time in shaping CD8 T cell transcriptional and epigenetic programs in cancer. 3) Define how inflammation and neuronal inputs affects T cell migration in the context of inflammatory insults. 4) Postdoctoral fellows will receive extensive one on one mentorship with Dr. Schenkel in order to facilitate career goals, foster independence, and to help develop writing and presentation skills. All duties and responsibilities are carried out in compliance with institutional policies, ethical research standards, and applicable federal and state regulations. *ELIGIBILITY REQUIREMENTS* An individual holding a recent (within three years) Ph.D. or equivalent doctorate (e.g., Sc.D., M.D., D.V.M.) in an appropriate field who is seeking a temporary appointment under the supervision of a faculty mentor, involving full-time laboratory-based research or scholarship in preparation for an academic or research career as an independent investigator. This appointment is not part of a clinical training program; individuals holding an M.D. degree or equivalent are not permitted to engage in patient care activity. *POSITION INFORMATION* MD Anderson offers full-time postdoc positions with a [salary ranging from $64,000 to $76,000](https://trainees.mdanderson.org/apply/mdaPostdoctoralFellowStipendFY24.pdf). depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent [benefits](https://www.utsystem.edu/offices/employee-benefits/insurance-0/eligibility), including medical, dental, [paid time off](https://www.mdanderson.org/about-md-anderson/employee-resources/leave.html), [retirement](https://www.utsystem.edu/offices/employee-benefits/ut-retirement-program/voluntary-retirement-programs), tuition benefits, educational opportunities, and individual and team recognition. Offsite work arrangements are subject to approval and may be modified or revoked at any time based on business needs, performance considerations, or regulatory requirements. This position may be responsible for maintaining the security and integrity of critical infrastructure, as defined in Section 113.001(2) of the Texas Business and Commerce Code and therefore may require routine reviews and screening. The ability to satisfy and maintain all requirements necessary to ensure the continued security and integrity of such infrastructure is a condition of hire and continued employment. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. [http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html](http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html) *FACULTY MENTOR* Jason Schenkel, PhD