Pittsburgh, PA, 15222, USA
1 day ago
Molecular Genomic Specialist I
UPMC Presbyterian is hiring a Molecular Genomic Specialist I to support the Molecular and Genomic Pathology Laboratory (MGP)! This is a daylight position working Monday through Friday - no weekends or holidays are required! The Molecular and Genomic Pathology Laboratory (MGP) is a dynamic state-of-the-art clinical laboratory that prides itself on providing the highest quality of patient care in the fields of inherited diseases, hematological malignancies, and solid tumors utilizing cutting-edge molecular testing platforms and informatics approaches exemplified by next-generation sequencing. MGP offers its staff a challenging and rewarding career by offering a wide variety of job responsibilities as well as opportunities to identify and build upon individual strengths. MGP promotes lab-wide collaboration and teamwork where each staff member is valued for the unique skill set they can offer the team! We are currently offering a generous sign-on bonus for those who qualify! Responsibilities: + Independently perform clinical testing in accordance with established SOPs. + Process all clinical, QC and PT specimens through clinical workflow. + Demonstrate high-level problem-solving skills and analytical abilities to successfully perform laboratory testing. + Accurately record relevant data and values in case folders and internal databases. + Process samples meticulously to avoid cross-contamination. + Meet established turn-around-time deadlines for clinical testing. + Maintain expertise in or knowledge of molecular biology techniques, including but not limited to: nucleic acid isolation, nucleic acid quantitation, PCR/RT-PCR/qPCR, Sanger sequencing, LOH, methylation analysis, MassARRAY MALDI-TOF, next-generation sequencing, etc. + Effectively communicate with other laboratory members including lab leadership. Maintain track of technical and professional development, including but not limited to attendance at seminars/webinars and participation in educational programs and activities. + Identify critical, abnormal and/or unacceptable results and follow-up according to established protocol. + Document all corrective action and follow-up with lead and/or supervisor. + Operate, perform routine maintenance on, and calibrate all laboratory equipment as required. + Identify problems with instrumentation, methodology, specimens, and/or supplies and follow-up according to established protocols. + Maintain proficiency in appropriate Laboratory Information Management Systems (LIMS). + Appropriately use automated and/or liquid handling machines for clinical testing. + Accurately and precisely analyze molecular assay results for final interpretation by medical staff. Molecular procedures are highly complex assays that have multiple steps over a series of several days. There are Quality Control check-points at each step, but the end result of every assay requires every technologist to evaluate assay performance as a whole as well as individual sample performance. Specific to molecular laboratories, technologists must: + Be able to pipet accurately and precisely. + Have scientific knowledge of molecular fundamentals and techniques, in order to understand the methodology of the assay and execute it properly both manually and using advanced instrumentation. + Possess high-level problem-solving skills for assay, instruments, controls, samples, and reagents/enzymes so they are able to notice, understand, and act upon performance trends of every step of every assay. + Understand basic molecular workflow principles and required proper precautions to ensure assay and specimen integrity.Molecular Genomic Specialist I: + BS degree, major in biological science field OR BS degree in chemical or physical science field with at least 1 year experience in clinical molecular laboratory AND 16 semester hours in chemistry (including at least 6 hours in inorganic chemistry), 16 semester hours in biology courses pertinent to the medical sciences, and 3 semester hours in mathematics. + One year of clinical molecular laboratory experience OR one year of experience through training in appropriate molecular laboratory coursework.Licensure, Certifications, and Clearances: + Act 34UPMC is an Equal Opportunity Employer/Disability/Veteran
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